We’re less than a month away from the opening kickoff of the 2023 Arizona Cardinals season, which could be a long one for fans of the franchise and backers at Arizona sports betting sites.
Ahead of the Cardinals’ season opener against the Washington Commanders at FedEx Field on Sept. 10, BetArizona.com compiled odds on when the Cardinals’ first loss will come in 2023.
The Cardinals are tied with Houston at BetMGM Arizona for the longest Super Bowl championship odds of any NFL team at +20000, with +1000 odds the team will go 0-17 this year.
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Cardinals First Loss Odds
| Week | Opponent | Odds | Percent Chance |
| 1 | at Washington Commanders | -200 | 66.7% |
| 2 | vs. New York Giants | +225 | 28.6% |
| 3 | vs. Dallas Cowboys | +5000 | 2.0% |
| 4 | at San Francisco 49ers | +9000 | 1.1% |
| 5 | vs. Cincinnati Bengals | +20000 | 0.5% |
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Cardinals Opening Stretch Appears Bleak
The Cardinals face an absolute gauntlet of an opening five-week stretch, playing five straight teams that went .500 or better to open the year.
With combined 2022 records of 54-21-1, Arizona will get no easy breaks when it comes to earning its first win of the season, which is why we gave it short odds to lose in each of those contests.
Arizona’s best loss odds come in Week 1 against Washington with -200 (or a 66.7% chance) of losing to the Commanders on the road Sept. 10. If fans want to use Arizona sportsbook promos to take a chance on the Cardinals, they are 6-point underdogs against Washington on Sept. 10.
The next best chance comes in Week 2 against the Giants, with +225 odds of Arizona falling in its home opener in Glendale.
For now, Cardinals fans can look forward to the team’s opener against the Commanders in September, holding onto the hope Arizona has what it takes to prove oddsmakers and analysts wrong.
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