Latest Arizona Cardinals Super Bowl Odds: October 2025

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Kyler Murray and the Cardinals haven’t reached the playoffs since 2021. After some early optimism in the Grand Canyon State, Arizona now sits at 2–4 and last in the NFC West. They’ll look to turn things around at home against the Green Bay Packers in Week 7.

Ahead of the matchup, the Arizona Cardinals are long shots to win the Super Bowl. We will be tracking Arizona's latest Super Bowl odds offered by some of the top Arizona sports betting operators all season long.

Cardinals' Super Bowl 60 Odds: October 14, 2025

The Cardinals' Super Bowl 60 odds are +20000 according to DraftKings Arizona. These odds will fluctuate throughout the season and differ across sportsbooks.

👑 Odds to Win Super Bowl 60+20000 (0.5% chance)
🏆 Odds to Win NFC+9000 (1.1% chance)
⭐ Odds to Win NFC West+6000 (1.6% chance)
🔥 Odds to Make Playoffs+920 (9.8% chance)
❌ Odds to Miss Playoffs-2000 (95.2% chance)
✅ Odds Last Updated:October 2025

Note that Arizona sports betting promos could improve your bankroll for some odds across other NFL teams. If you’re looking to get in on the NFL prop action, Trey McBride is +160 to score an anytime touchdown in Week 7.

21+. New customers in AZ, CO, CT, DC, IA, IL, IN, KS, KY, LA, MA, MD, MI, NC, NJ, OH, PA, TN, VT, VA, WV, or WY: wager $10+ cash on any market with odds of -500 or longer to be eligible to receive $50 in FanCash each day for your first five (5) days. Terms, including FanCash terms apply - see Fanatics Sportsbook app. Gambling Problem? Call or Text 1-800-GAMBLER, 1-800-NEXT-STEP (AZ), 1-800-9-WITH-IT (IN), 1-888-532-3500 (VA).

Cardinals' Super Bowl Odds vs NFC West

Right now, the Cardinals have the longest odds in the NFC West to win the Super Bowl. The Los Angeles Rams lead the division with the best Super Bowl 60 odds at +1400. Early in the season, Arizona faced back-to-back divisional tests, and after dropping both, their chances to win the division and the Super Bowl have taken a hit. They are looking to bounce back with a win in Week 7 against the Packers.

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Latest Updates Impacting Cardinals' Odds to Win SB LX

Throughout the season, the Cardinals’ Super Bowl odds will fluctuate based on player performance and injuries. Below, you’ll find the latest updates affecting those odds:

  • 🗓️ October 11: The Cardinals place P Blake Gilikin on injured reserve.
  • 🗓️ October 8: TE Tip Reiman placed on injured reserve.
  • 🗓️ October 4: Arizona activates DL Bilal Nichols from the injured reserve list.
  • 🗓️ October 1: The Cards place RB Trey Benson on injured reserved.
  • 🗓️ September 29: Arizona signs RB Michael Carter to the active roster and designates.
  • 🗓️ September 21: RB James Connor suffers an ankle injury in Week 3’s loss to San Francisco and will miss the rest of the season. 
  • 🗓️ September 10: The Cardinals place S Joey Blount on IR (concussion).
  • 🗓️ September 7: Arizona wins first game of the season, 20-13 against New Orleans.
  • 🗓️ August 28: The Cards place DL Justin Jones on injured reserve.
  • 🗓️ August 26: Arizona place DLs Walter Nolen III and Bilal Nichols, and LB BJ Ojulari on the PUP list.
  • 🗓️ August 7: The Cardinals sign OL Will Hernandez to a one-year contract.
  • 🗓️ June 10: DL Walter Nolen III signs a four-year contract with Arizona.

As Arizona makes more moves, this section will be updated. Check back regularly to stay informed on the major moves made by the Cardinals.

 

  • 🗓️ May 21: The Cardinals sign LB J.J. Russell to a one-year contract.
  • 🗓️ April 24: Arizona drafts DT Walter Nolen from Ole Miss in the first round of the 2025 draft.
  • 🗓️ April 17: DE Calais Campbell signs with Arizona.
  • 🗓️ April 3: The Cardinals sign OL Jake Curhan and re-sign OL Kelvin Beachum.
  • 🗓️ March 17: WR Zay Jones re-signs with Arizona.
  • 🗓️ March 12: The Cards sign OLB Josh Sweat, LB Akeem Davis-Gaither, DL Dalvin Tomlinson, and QB Jacoby Brissett.
  • 🗓️ March 7: Arizona re-signs LS Aaron Brewer to a one-year contract and S Joey Blount to a two-year contract.
  • 🗓️ January 5: The Cardinals finish the season with an 8-9 record after defeating the San Francisco 49ers in Week 18, 47-24.
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Kyler Murray throws the ball

Arizona Cardinals' 2025 Schedule

The Arizona Cardinals have one of the easiest schedules in the NFL based on last season’s strength of schedule, with their opponents combining for a .457 winning percentage. In Week 7, Arizona is a 6.5-point underdog against the 3-1 Packers.

Cardinals ScheduleLineResult
Week 1 at SaintsAZ -6.5, ML -298⭐ W 20-13
Week 2 vs PanthersAZ -6.5, ML -298⭐ W 27-22
Week 3 at 49ersAZ +3, ML +136❌ L 16-15
Week 4 vs SeahawksAZ -1.5, ML -115❌ L 23-20
Week 5 vs TitansAZ -8.5 ML -410❌ L 22-21
Week 6 at ColtsAZ +7, ML +370❌ L 31-27
Week 7 vs PackersAZ +6.5, ML +275TBD
Week 8 BYE--
Week 9 at CowboysAZ +1.5, ML +102TBD
Week 10 at SeahawksAZ +1.5, ML +100TBD
Week 11 vs 49ersAZ +1.5, ML +100TBD
Week 12 vs JaguarsAZ -3, ML -155TBD
Week 13 at BuccaneersAZ +3.5, ML +150TBD
Week 14 vs RamsAZ +1.5, ML -102TBD
Week 15 at TexansAZ +2.5, ML +110TBD
Week 16 vs FalconsAZ -3.5, ML -175TBD
Week 17 at BengalsAZ +3.5, ML -110TBD
Week 18 at RamsAZ +3.5, ML +145TBD
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Key Contributors Toward Cardinals Super Bowl Odds

Expectations for the Cards have fallen short so far this season. While the defense has been strong, the offense is struggling. Consistency from the quarterback, Trey McBride, and Marvin Harrison Jr. will be key, and the team needs to find a way to replace the production lost with star RB James Conner out for the season. The offense has gotten off to slow starts in games and must play with more urgency if Arizona wants to turn things around. 

Injuries have also been a challenge early in the season. With Conner out and Trey Benson on injured reserve, the Cardinals signed RB Michael Carter from the practice squad to help in the backfield. On the bright side, DT Bilal Nichols is returning from the PUP list, and the team is expecting updates this week on rookie Walter Nolen III’s hopeful return from IR.

Cardinals Super Bowl Prediction and LX Outlook

Kyler Murray stayed healthy in 2024, fueling a surprising resurgence for Arizona. Even so, the Cardinals fell short of the playoffs. Murray is back dealing with injuries, with Jacoby Brissett stepping in to lead the offense.

Arizona had an active offseason, signing key free agents and bolstering its defense through the draft. Before the draft, the Cardinals’ Super Bowl odds sat at +7000. Following a strong draft, those odds have improved slightly to +5000. But sitting at 2-3, Arizona’s odds have slipped to +20000.

Cardinals' 2025 Draft Class

Round 1 - DT Walter Nolen (Ole Miss)
Round 2 - CB Will Johnson (Michigan)
Round 3 - DT Jordan Burch (Oregon)
Round 4 - LB Cody Simon (Ohio State)
Round 5 - CB Denzel Burke (Ohio State)
Round 6 - OG Hayden Conner (Texas)
Round 7 - S Kitan Crawford (Nevada)

According to +920 odds at DraftKings, Arizona has a 9.8% chance of making the playoffs. For a closer look at the Cardinals' playoff chances, we have a separate article tracking Arizona's postseason picture.

Where Can I Bet on the Arizona Cardinals to Win the Super Bowl?

DraftKings, BetMGM, Caesars Sportsbook, and FanDuel are among the most trusted sportsbooks in the industry. Each currently lists odds for the Cardinals and each of the NFL’s 32 teams to win Super Bowl LX and more futures for the 2025 season.

In the state of Arizona, sports betting is legal, both online and at retail locations. Bettors must be at least 21 years old to legally wager on the Cardinals to win the Super Bowl or any other sports bet.

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Cardinals Super Bowl History

The Arizona Cardinals are the oldest franchise in the NFL, yet they’ve only made one Super Bowl appearance, Super Bowl XLIII against the Pittsburgh Steelers. battle filled with memorable moments, including Larry Fitzgerald’s spectacular 64-yard catch-and-run touchdown that gave the Cardinals the lead late in the game. But that highlight was overshadowed by a game-winning touchdown from Ben Roethlisberger to Santonio Holmes with less than a minute left.

Arizona got into range for a Hail Mary attempt, but Kurt Warner was sacked and lost a fumble to secure the 27-23 win for the Steelers. Adding salt to the wound, the following week, Fitzgerald came down with what was a similar pass to the one Warner would have thrown for a touchdown in the Pro Bowl. If only...

Have the Cardinals Ever Won the Super Bowl?

No. The Arizona Cardinals have never won the Super Bowl. They’re one of just 12 NFL teams to have never hoisted the Lombardi Trophy. The Cardinals played in Super Bowl XLIII, losing to the Pittsburgh Steelers in their only Super Bowl appearance. Despite a long history, the franchise is still chasing its first Super Bowl title.

How Many Times Have the Cardinals Won the Super Bowl?

Zero. Arizona has made one Super Bowl appearance and could not secure the Lombardi Trophy. Joining Arizona among teams to never win the Super Bowl are the Buffalo Bills, Houston Texans, Tennessee Titans, Jacksonville Jaguars, Cleveland Browns, Cincinnati Bengals, Los Angeles Chargers, Detroit Lions, Minnesota Vikings, Carolina Panthers, and Atlanta Falcons.

Have the Cardinals Ever Been to the Super Bowl?

Yes, the Arizona Cardinals have one Super Bowl appearance. In Super Bowl XLIII, the Cardinals fell to the Pittsburgh Steelers in Tampa, 27-23. Pittsburgh wide receiver Santonio Holmes was named the game’s MVP.

Other than the 2008-09 season, the closest the Cardinals have come to the Super Bowl is when they made the NFC Championship during the 2015-16 season. Arizona lost 49-15 to the Carolina Panthers and has yet to advance past the wild-card round since.

How Many Times Have the Cardinals Been to the NFC Championship Game?

The Cardinals have been to the NFC Championship Game just twice. They beat the Philadelphia Eagles at home to reach Super Bowl XLIII in the 2008-09 season and fell on the road to the Carolina Panthers 49-15 in a bid to reach Super Bowl 50.

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Arizona Cardinals' Super Bowl FAQs

Author

Wes Roesch

Wes is an editor and writer for BetArizona.com. Based out of the Kansas City area, Wes has covered sports professionally since 2015 with a strong emphasis on sports betting and the NFL, though he's also covered pro wrestling, UFC, college sports and more.

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