Latest Arizona Cardinals Super Bowl Odds: December 2025

Cardinals' Super Bowl 60 Odds: December 4, 2025

The Cardinals' Super Bowl 60 odds are off the board at DraftKings Arizona. The Los Angeles Rams have the best odds to win it all this season.

Note that Arizona sports betting promos could improve your bankroll for some odds across other NFL teams. If you’re looking to get in on the NFL prop action, Trey McBride is +135 to score an anytime touchdown in Week 14.

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Cardinals' Super Bowl Odds vs NFC West

As mentioned above, the Cardinals’ odds to win the Super Bowl are off the board after they were eliminated from the playoffs. The Los Angeles Rams lead the division and the NFL with the best Super Bowl 60 odds at +450. The Seattle Seahawks have the next best odds at +750, while the 49ers’ odds to win the Super Bowl sit at +2800.

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Latest Updates Impacting Cardinals' Odds to Win SB LX

Throughout the season, the Cardinals’ Super Bowl odds will fluctuate based on player performance and injuries. Below, you’ll find the latest updates affecting Arizona's odds:

• 🗓️ November 30: The Cardinals lose to the Buccaneers, eliminating them from the playoffs.
• 🗓️ November 26: Arizona designates OL Christian Jones to return from injured reserve.
• 🗓️ November 19: The Cards designate RB Trey Benson to return from injured reserve.
• 🗓️ November 15: Arizona places LB Mack Wilson Sr. on injured reserve and activates OLB BJ Ojulari from the PUP list.
• 🗓️ November 9: WR Zay Jones placed on injured reserve.
• 🗓️ November 5: The Cardinals place QB Kyler Murray on injured reserve.
• 🗓️ November 3: Arizona reinstates DL Walter Nolen III from the physically unable to perform list and CB Garrett Williams from injured reserve.
• 🗓️ October 11: The Cards place P Blake Gilikin on injured reserve.
• 🗓️ October 8: TE Tip Reiman placed on injured reserve.
• 🗓️ October 4: Arizona activates DL Bilal Nichols from the injured reserve list.
• 🗓️ October 1: The Cards place RB Trey Benson on injured reserved.

As Arizona makes more moves, this section will be updated. Check back regularly to stay informed on the major moves made by the Cardinals.

Arizona Cardinals' 2025 Schedule

The Arizona Cardinals have one of the easiest schedules in the NFL based on last season’s strength of schedule, with their opponents combining for a .457 winning percentage. In Week 13, Arizona is a 2.5-point underdog against the 6-5 Bucs.

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Key Contributors Toward Cardinals Super Bowl Odds

The Arizona Cardinals have fallen short of expectations this season. On offense, injuries and inconsistency along the offensive line have stalled both the run game and passing attack. Defensively, the unit has struggled to close out games, with several losses coming by narrow margins in the final minutes of the fourth quarter as they failed to get key stops or finish drives. Things turned around in Week 9, when the Cardinals delivered their best performance of the season on both sides of the ball. But fell flat in Week 10, falling 44-22 to the Seahawks and 41-22 to the 49ers in Week 11.

With Murray on IR, it looks like QB Jacoby Brissett will be taking over as the team’s No. 1 quarterback. On offense, Trey McBride, Michael Wilson, and Marvin Harrison Jr. have proven to be reliable targets. Defensively, the unit is finally coming together to make big stops. After losing back to back divisional games, it’s a crucial stretch for the Cardinals’ playoff chances.

Cardinals Super Bowl Prediction and LX Outlook

Kyler Murray stayed healthy in 2024, fueling a surprising resurgence for Arizona. Even so, the Cardinals fell short of the playoffs. Murray is back on IR, with Jacoby Brissett stepping in to lead the offense.

Arizona had an active offseason, signing key free agents and strengthening its defense through the draft. Before the draft, the Cardinals’ Super Bowl odds sat at +7000. Following a strong draft, those odds improved slightly to +5000. But now, with just three wins so far, the Cardinals’ odds to win Super Bowl 60 are off the board.

Cardinals' 2025 Draft Class

Round 1 - DT Walter Nolen (Ole Miss)
Round 2 - CB Will Johnson (Michigan)
Round 3 - DT Jordan Burch (Oregon)
Round 4 - LB Cody Simon (Ohio State)
Round 5 - CB Denzel Burke (Ohio State)
Round 6 - OG Hayden Conner (Texas)
Round 7 - S Kitan Crawford (Nevada)

The Cardinals' playoff chances are off the board after the team was eliminated from contention in Week 13. If the season ended today, Arizona would hold the ninth overall pick in the 2026 draft.

Where Can I Bet on the Arizona Cardinals to Win the Super Bowl?

DraftKings, BetMGM, Caesars Sportsbook, and FanDuel are among the most trusted sportsbooks in the industry. Each currently lists odds for upcoming Cardinals games, the latest Super Bowl LX odds, and other futures for the 2025–26 season.

In Arizona, sports betting is legal both online and at retail locations. Bettors must be at least 21 years old to legally wager on the Cardinals to win the Super Bowl (when odds are available) or on any other sports bet.

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Cardinals Super Bowl History

The Arizona Cardinals are the oldest franchise in the NFL, yet they’ve only made one Super Bowl appearance, Super Bowl XLIII against the Pittsburgh Steelers. battle filled with memorable moments, including Larry Fitzgerald’s spectacular 64-yard catch-and-run touchdown that gave the Cardinals the lead late in the game. But that highlight was overshadowed by a game-winning touchdown from Ben Roethlisberger to Santonio Holmes with less than a minute left.

Arizona got into range for a Hail Mary attempt, but Kurt Warner was sacked and lost a fumble to secure the 27-23 win for the Steelers. Adding salt to the wound, the following week, Fitzgerald came down with what was a similar pass to the one Warner would have thrown for a touchdown in the Pro Bowl. If only...

Have the Cardinals Ever Won the Super Bowl?

No. The Arizona Cardinals have never won the Super Bowl. They’re one of just 12 NFL teams to have never hoisted the Lombardi Trophy. The Cardinals played in Super Bowl XLIII, losing to the Pittsburgh Steelers in their only Super Bowl appearance. Despite a long history, the franchise is still chasing its first Super Bowl title.

How Many Times Have the Cardinals Won the Super Bowl?

Zero. Arizona has made one Super Bowl appearance and could not secure the Lombardi Trophy. Joining Arizona among teams to never win the Super Bowl are the Buffalo Bills, Houston Texans, Tennessee Titans, Jacksonville Jaguars, Cleveland Browns, Cincinnati Bengals, Los Angeles Chargers, Detroit Lions, Minnesota Vikings, Carolina Panthers, and Atlanta Falcons.

Have the Cardinals Ever Been to the Super Bowl?

Yes, the Arizona Cardinals have one Super Bowl appearance. In Super Bowl XLIII, the Cardinals fell to the Pittsburgh Steelers in Tampa, 27-23. Pittsburgh wide receiver Santonio Holmes was named the game’s MVP.

Other than the 2008-09 season, the closest the Cardinals have come to the Super Bowl is when they made the NFC Championship during the 2015-16 season. Arizona lost 49-15 to the Carolina Panthers and has yet to advance past the wild-card round since.

How Many Times Have the Cardinals Been to the NFC Championship Game?

The Cardinals have been to the NFC Championship Game just twice. They beat the Philadelphia Eagles at home to reach Super Bowl XLIII in the 2008-09 season and fell on the road to the Carolina Panthers 49-15 in a bid to reach Super Bowl 50.

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Author

Wes Roesch

Editor & Writer

@WesRoesch

Wes is an editor and writer for BetArizona.com. Based out of the Kansas City area, Wes has covered sports professionally since 2015 with a strong emphasis on sports betting and the NFL, though he's also covered pro wrestling, UFC, college sports and more.