The first Arizona Cardinals Monday Night Football contest since new Arizona sports betting apps launched did a number on the home team’s Super Bowl odds.
That’s because the Cardinals lost to the Los Angeles Rams 30-23, falling to 3-3 at home and 10-3 for the year — knocking Arizona to the No. 3 seed in the NFC.
The Cardinals have five days to shake off their first loss in almost a month, as they head to the Motor City to play the 1-11-1 Detroit Lions at 11 a.m. Arizona time Sunday on FOX.
Must be 21+ and physically present in AZ, CO, IL, IN, IA, KS, KY, LA, ME, MD, MA, MI, MO, NJ, NY, NC, OH, PA, TN, VA, WV, WY or Washington, DC. New users only. Must register using eligible promo code. First wager after registration must qualify. Min. Odds: -500. Max. Bonus Bet: $250. Awarded as non-withdrawable Bonus Bet that expires 14 days after receipt. Bonus Bet amount not returned for winning bets. Void where prohibited. See http://Caesars.com/promos for full terms. Know When To Stop Before You Start®. Gambling Problem? CO, IL, KY, MD, MI, MO, NJ, OH, TN, VA, WV, WY, KS (Affiliated with Kansas Crossing Casino), ME (Licensed through the Mi’kmaq Nation, Penobscot Nation, and Houlton Band of Maliseet Indians, federally recognized tribes located in the State of Maine), NC (Licensed through Tribal Casino Gaming Enterprise), PA (Affiliated with Harrah's Philadelphia): If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) or MD: visit http://mdgamblinghelp.org or WV: visit http://1800gambler.net ; AZ: Call 1-800-NEXT-STEP; IN: Call 1-800-9-WITH-IT; IA: Call 1-800-BETSOFF; LA (Licensed through Horseshoe Bossier City and Caesars New Orleans), Washington, DC (OLG Class A licensed Operator): Call 1-800-522-4700. ©2025, Caesars Entertainment Gambling Problem? Call 1-800-GAMBLER DC, LA: Call 1-800-522-4700 MA: Call 1-800-327-5050 or visit http://gamblinghelplinema.org NY: Call 877-8-HOPENY or text HOPENY (467369)
Cardinals Sizable Road Favorites Over Lions
Arizona sportsbooks aren’t expecting Kyler Murray and company to suffer much of a hangover in Detroit, with Arizona listed as a double-digit favorite.
At BetMGM Arizona, the Cardinals are at -13.5 (-110).
Meanwhile, DraftKings Sportsbook Arizona has the Cardinals listed at -14 (-110), and FanDuel Sportsbook Arizona has Arizona at -13.5 (-114).
For those looking to make a moneyline wager, BetMGM Arizona has the Cardinals at -833, while DraftKings Sportsbook Arizona has them at -800, and FanDuel Sportsbook Arizona has the visitors at -820.
All three have the over/under at 47.5 (-110) total points.
Gambling problem? Call 1-800-GAMBLER (Available in the US) Call 877-8-HOPENY or text HOPENY (467369) (NY) Call 1-800-327-5050 (MA), 1-800-NEXT-STEP (AZ), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR) 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. This promotional offer is not available in DC, Mississippi, New York, Nevada, Ontario, or Puerto Rico.
Arizona’s Super Bowl Odds Take a Hit
Monday night’s loss to the Rams dented Arizona’s Super Bowl betting odds.
Four sportsbooks — DraftKings Sportsbook Arizona, FanDuel Sportsbook Arizona, TwinSpires Sportsbook, and Unibet Arizona — have the Cardinals at +1000 to win Super Bowl LVI.
Both BetMGM Arizona and Caesars Sportsbook Arizona have the Cardinals at +900, ranking fifth overall in the NFL.
Before Monday’s loss, FanDuel Sportsbook Arizona listed the Cardinals among its top three Super Bowl favorites at +750.
Must be 21+ to participate. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, KY, MI, NJ, OH, PA, IL, TN, VA, VT), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), visit www.mdgamblinghelp.org (MD), 1-800-522-4700 (WY), or visit www.1800gambler.net (WV). GamblingHelpLineMA.org or call (800) 327-5050 for 24/7 support (MA). Call 1-877-8HOPE-NY or text HOPENY (467369) (NY).
Stacking up the Rest of the Schedule
The Cardinals close out the regular season with games against Indianapolis and Seattle at home, sandwiched between a road game against Dallas. Both the Colts (7-6) and Cowboys (9-4) have winning records. The Seahawks are 5-8.
Arizona’s game against Indianapolis takes place on Christmas Day at 6:15 p.m. Arizona time on the NFL Network.
After losing as a 3.5-point favorite Monday night, the Cardinals are 9-4-0 against the spread this season.
![quote]( "quote")
