Latest Arizona Cardinals Injury Report: Week 2 Update

Latest Cardinals Injury Report: September 13, 2025

The biggest injury news at the start of the season is rookie Walter Nolen III (calf), who starts the year on the Physically Unable to Perform (PUP) list. He isn’t eligible to return until after Week 4, making October 6 against the 49ers his earliest possible debut.

Below is the latest Arizona Cardinals injury report:

Some Arizona sports betting apps will update you on a player’s injury status, but it’s always smart to double-check before placing any bets. Staying informed can give you a real edge when betting on Cardinals games this season.

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List of Notable Arizona Cardinals 2025 Injuries

The outside linebacker group, anchored by Josh Sweat, will be tested early. First‑round pick Walter Nolen, defensive lineman Bilal Nichols, and edge rusher BJ Ojulari are all on the active/PUP list. Depth will be key, and the Cardinals planned ahead by adding veterans like Calais Campbell and Dalvin Tomlinson, while also re‑signing L.J. Collier. Arizona’s secondary took the biggest hit, with Sean Murphy‑Bunting and Starling Thomas V both out for the season. 

For Week 2, linebacker Zavin Collins and punter Blake Gillikin are listed as questionable. Offensive lineman Will Hernandez is also questionable, while tight end Tip Reiman and linebacker Cody Simon have been ruled out.

Keep an eye on this list as the Cardinals gear up for their 2025 Week 2 matchup against the Carolina Panthers.

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Wes Roesch

Editor & Writer

@WesRoesch

Wes is an editor and writer for BetArizona.com. Based out of the Kansas City area, Wes has covered sports professionally since 2015 with a strong emphasis on sports betting and the NFL, though he's also covered pro wrestling, UFC, college sports and more.