Arizona Cardinals Injury Report: Week 6 Injuries

Latest Arizona Cardinals Injury Report: Week 6 Update

The Arizona Cardinals are one of the most intriguing teams to watch this season, opening 2025 with a 2-3 record. They will travel to Indy to take on the Colts on October 12.

We’re tracking the latest Arizona Cardinals injury report as the team gears up for Week 5 of the 2025 NFL season. Bettors will want to keep a close watch, especially if you’re using Arizona sports betting promos. These injuries could heavily influence the Cardinals’ playoff chances. Stay tuned throughout the season for roster moves, injury updates, and more on the Cardinals’ 2025 campaign.

Latest Cardinals Injury Report: October 13, 2025

The biggest injury news at the start of the season is rookie Walter Nolen III (calf), who starts the year on the Physically Unable to Perform (PUP) list. He was eligible to return after Week 4, but no timetable has been set for his comeback.

Below is the latest Arizona Cardinals injury report:

Some Arizona sports betting apps will update you on a player’s injury status, but it’s always smart to double-check before placing any bets. Staying informed can give you a real edge when betting on Cardinals games this season.

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List of Notable Arizona Cardinals 2025 Injuries

James Conner is already sidelined for the year, and now RB Trey Benson has been placed on IR, leaving Emari Demercado to handle the running back role alongside Bam Knight and Michael Carter.

As for this week, defensive lineman Darius Robinson has been ruled out for Week 6, while Evan Brown and Max Melton are listed as questionable. In fact, several Cardinals are questionable, including QB Kyler Murray, WR Zay Jones, Punter Blake Gillikin, and LB Cody Simon.

Keep an eye on this list as the Cardinals gear up for their 2025 Week 6 matchup against the Colts.

Read More Cardinals Coverage:

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Cardinals Injury Report FAQs

The first injury report of the week is released on Wednesdays before Sunday games, followed by the final report on Friday. For games played on days other than Sunday, like Thursday or Monday night, the injury report schedule is different. Teams are required to submit a final injury report 90 minutes before kickoff.

Arizona Cardinals quarterback Kyler Murray has been healthy all season but is now on the injury report as questionable for Week 6. The starting QB missed practice all week but returned on Friday, leaving his status for Sunday uncertain. If he can’t play, Jacoby Brissett will take over.

Author

Wes Roesch

Editor & Writer

Wes is an editor and writer for BetArizona.com. Based out of the Kansas City area, Wes has covered sports professionally since 2015 with a strong emphasis on sports betting and the NFL, though he's also covered pro wrestling, UFC, college sports and more.