Latest Arizona Cardinals Injury Report: Week 15 Update

Latest Cardinals Injury Report: December 17, 2025

Kyler Murray was hoping to make his return in Week 9, but after missing the game, he is now on IR and will miss the remainder of the season. Head coach Jonathan Gannon confirmed that Jacoby Brissett will continue as the starter moving forward. Brissett and the Cardinals have lost five straight games, eliminating them from the postseason.

Below is the latest Week 15 Arizona Cardinals injury report:

Some Arizona sports betting apps will update you on a player’s injury status, but it’s always smart to double-check before placing any bets. Staying informed can give you a real edge when betting on Cardinals games this season.

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List of Notable Arizona Cardinals 2025 Injuries

As noted above, QB Kyler Murray is on IR, joining RB James Conner, TE Tip Reiman, WR Zay Jones, and other. WR Greg Dortch was also recently placed on IR, tightening the screws on Arizona’s offensive depth. 

For the upcoming matchup against the Texans, the Arizona Cardinals have eight players ruled out, including WR Marvin Harrison, CB Max Melton, S Dadrion Taylor-Demerson, LT Paris Johnson Jr., and WR Xavier Weaver. In addition, RB Emari Demercado, OT Walter Nolen, and TE Elijah Higgins are questionable.

For the Texans, they only list TE Harrison Bryant, RB Nick Chubb, WR Justin Watson, and LB E.J. Speed as questionable ahead of Week 15 kickoff.

Read More Cardinals Coverage:

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Wes Roesch

Editor & Writer

@WesRoesch

Wes is an editor and writer for BetArizona.com. Based out of the Kansas City area, Wes has covered sports professionally since 2015 with a strong emphasis on sports betting and the NFL, though he's also covered pro wrestling, UFC, college sports and more.